POLRMT

POLRMT
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3SPA, 4BOC
Identifiers
Aliases	POLRMT, APOLMT, MTRNAP, MTRPOL, h-mtRPOL, polymerase (RNA) mitochondrial, RNA polymerase mitochondrial, COXPD55
External IDs	OMIM: 601778; MGI: 1915843; HomoloGene: 37996; GeneCards: POLRMT; OMA:POLRMT - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	633,537 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	79,582,415 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; apex of heart; ; testicle; ; mucosa of transverse colon; ; gonad; ; muscle of thigh; ; right lobe of liver; ; gastrocnemius muscle; ; anterior pituitary;
	Top expressed in
	right ventricle; ; internal carotid artery; ; external carotid artery; ; temporal muscle; ; primary oocyte; ; sternocleidomastoid muscle; ; triceps brachii muscle; ; muscle of thigh; ; motor neuron; ; digastric muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-directed 5'-3' RNA polymerase activity; transferase activity; DNA binding; nucleotidyltransferase activity; protein binding; RNA binding; mitochondrial promoter sequence-specific DNA binding; sequence-specific DNA binding;
Cellular component	mitochondrial matrix; mitochondrial nucleoid; mitochondrion; mitochondrial DNA-directed RNA polymerase complex; protein-containing complex;
Biological process	mitochondrial transcription; transcription initiation from mitochondrial promoter; mitochondrion organization; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	5442
	216151
	ENSG00000099821
	ENSMUSG00000020329
	O00411
	Q8BKF1
	NM_005035
	NM_172551
	NP_005026
NP_766139; NP_001394721; NP_001394722; NP_001394723; NP_001394724;
	NP_001394725; NP_001394726; NP_001394727; NP_001394728
	Wikidata
View/Edit Human	View/Edit Mouse

DNA-directed RNA polymerase, mitochondrial is an enzyme that in humans is encoded by the POLRMT gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000099821 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020329 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tiranti V, Savoia A, Forti F, D'Apolito MF, Centra M, Rocchi M, Zeviani M (Jul 1997). "Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database". Hum Mol Genet. 6 (4): 615–25. doi:10.1093/hmg/6.4.615. PMID 9097968.
^ "Entrez Gene: POLRMT polymerase (RNA) mitochondrial (DNA directed)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000099821 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020329 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9097968-5] Tiranti V, Savoia A, Forti F, D'Apolito MF, Centra M, Rocchi M, Zeviani M (Jul 1997). "Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database". Hum Mol Genet. 6 (4): 615–25. doi:10.1093/hmg/6.4.615. PMID 9097968.

[entrez-6] "Entrez Gene: POLRMT polymerase (RNA) mitochondrial (DNA directed)".

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