PRC1

PRC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3NRX, 3NRY, 4L3I, 4L6Y
Identifiers
Aliases	PRC1, ASE1, protein regulator of cytokinesis 1
External IDs	OMIM: 603484; MGI: 1858961; HomoloGene: 37868; GeneCards: PRC1; OMA:PRC1 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	90,995,629 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	80,316,259 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; gonad; ; testicle; ; left testis; ; right testis; ; bone marrow; ; stromal cell of endometrium; ; mucosa of transverse colon; ; bone marrow cells;
	Top expressed in
	primary oocyte; ; secondary oocyte; ; spermatocyte; ; zygote; ; tail of embryo; ; ventricular zone; ; genital tubercle; ; morula; ; morula; ; endothelial cell of lymphatic vessel;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein kinase binding; identical protein binding; kinesin binding; microtubule binding; protein binding;
Cellular component	spindle; cytosol; spindle pole; microtubule; spindle microtubule; contractile ring; cytoskeleton; nucleus; midbody; cytoplasm;
Biological process	microtubule bundle formation; cell cycle; cell division; microtubule cytoskeleton organization; mitotic spindle elongation; positive regulation of cell population proliferation; cytokinesis; regulation of cytokinesis;
	Sources:Amigo / QuickGO
Orthologs
	9055
	233406
	ENSG00000198901
	ENSMUSG00000038943
	O43663
	Q99K43
	NM_001267580; NM_003981; NM_199413; NM_199414
	NM_001285997; NM_001285998; NM_145150; NM_001374624
	NP_001254509; NP_003972; NP_955445
NP_001272926; NP_001272927; NP_660132; NP_001361553; NP_001369314;
	NP_001369315; NP_001369316; NP_001369317; NP_001369318; NP_001369319
	Wikidata
View/Edit Human	View/Edit Mouse

Protein Regulator of cytokinesis 1 (PRC1) is a protein that in humans is encoded by the PRC1 gene and is involved in cytokinesis.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198901 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038943 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Jiang W, Jimenez G, Wells NJ, Hope TJ, Wahl GM, Hunter T, Fukunaga R (1998). "PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis". Mol. Cell. 2 (6): 877–85. doi:10.1016/S1097-2765(00)80302-0. PMID 9885575.
^ "Entrez Gene: PRC1 protein regulator of cytokinesis 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000198901 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038943 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9885575-5] Jiang W, Jimenez G, Wells NJ, Hope TJ, Wahl GM, Hunter T, Fukunaga R (1998). "PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis". Mol. Cell. 2 (6): 877–85. doi:10.1016/S1097-2765(00)80302-0. PMID 9885575.

[entrez-6] "Entrez Gene: PRC1 protein regulator of cytokinesis 1".

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