PSCA (gene)

PSCA
Identifiers
AliasesPSCA, PRO232, prostate stem cell antigen, lncPSCA
External IDsOMIM: 602470; MGI: 1919623; HomoloGene: 4150; GeneCards: PSCA; OMA:PSCA - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005672

NM_028216

RefSeq (protein)

NP_005663

NP_082492

Location (UCSC)Chr 8: 142.67 – 142.68 MbChr 15: 74.59 – 74.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Prostate stem cell antigen is a protein that in humans is encoded by the PSCA gene.[5][6]

This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene has a nonsynonymous nucleotide polymorphism at its start codon.[6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000167653Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022598Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Reiter RE, Gu Z, Watabe T, Thomas G, Szigeti K, Davis E, et al. (February 1998). "Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer". Proceedings of the National Academy of Sciences of the United States of America. 95 (4): 1735–40. Bibcode:1998PNAS...95.1735R. doi:10.1073/pnas.95.4.1735. PMC 19171. PMID 9465086.
  6. ^ a b "Entrez Gene: PSCA prostate stem cell antigen".