PTK7

PTK7
Identifiers
Aliases	PTK7, CCK-4, CCK4, protein tyrosine kinase 7 (inactive)
External IDs	OMIM: 601890; MGI: 1918711; HomoloGene: 43672; GeneCards: PTK7; OMA:PTK7 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	43,161,719 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	46,940,430 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; body of uterus; ; left ovary; ; right ovary; ; canal of the cervix; ; ectocervix; ; right uterine tube; ; left uterine tube; ; right testis; ; left testis;
	Top expressed in
	tail of embryo; ; lip; ; molar; ; ventricular zone; ; epiblast; ; genital tubercle; ; embryo; ; dermis; ; embryo; ; left lung lobe;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein kinase activity; protein binding; ATP binding; coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway;
Cellular component	integral component of membrane; membrane; cell-cell junction; focal adhesion; plasma membrane; cell junction; integral component of plasma membrane;
Biological process	actin cytoskeleton reorganization; cellular response to retinoic acid; ventricular septum development; convergent extension; establishment of planar polarity; wound healing; Wnt signaling pathway; coronary vasculature development; planar cell polarity pathway involved in neural tube closure; protein phosphorylation; heart development; establishment of epithelial cell apical/basal polarity; cell adhesion; neural tube closure; axis elongation; cochlea morphogenesis; positive regulation of neuron projection development; canonical Wnt signaling pathway; lung-associated mesenchyme development; cell migration; signal transduction; positive regulation of canonical Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	5754
	71461
	ENSG00000112655
	ENSMUSG00000023972
	Q13308
	Q8BKG3
NM_001270398; NM_002821; NM_152880; NM_152881; NM_152882;
	NM_152883
	NM_175168
	NP_001257327; NP_002812; NP_690619; NP_690620; NP_690621
	NP_780377
	Wikidata
View/Edit Human	View/Edit Mouse

Tyrosine-protein kinase-like 7 also known as colon carcinoma kinase 4 (CCK4) is a receptor tyrosine kinase that in humans is encoded by the PTK7 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000112655 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023972 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mossie K, Jallal B, Alves F, Sures I, Plowman GD, Ullrich A (Nov 1995). "Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family". Oncogene. 11 (10): 2179–84. PMID 7478540.
^ "Entrez Gene: PTK7 PTK7 protein tyrosine kinase 7".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000112655 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000023972 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7478540-5] Mossie K, Jallal B, Alves F, Sures I, Plowman GD, Ullrich A (Nov 1995). "Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family". Oncogene. 11 (10): 2179–84. PMID 7478540.

[entrez-6] "Entrez Gene: PTK7 PTK7 protein tyrosine kinase 7".

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