Palazzo Valguarnera-Gangi is an urban palace, first of the Princes Valguarnera and then of the Princes Gangi, situated in the Piazza Croce dei Vespri, in the ancient quarter of the Kalsa in the city of Palermo, region of Sicily, Italy. The palace still retains its original rich Rococo interior decoration, and is located a block south of the church of Sant'Anna la Misericordia.