Palifermin

Palifermin
Clinical data
AHFS/Drugs.comMonograph
MedlinePlusa605017
Routes of
administration
intravenous bolus injection
ATC code
Identifiers
CAS Number
IUPHAR/BPS
DrugBank
ChemSpider
  • none
UNII
ChEMBL
ECHA InfoCard100.118.147 Edit this at Wikidata
Chemical and physical data
FormulaC721H1142N202O204S9
Molar mass16192.82 g·mol−1
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Palifermin (trade name Kepivance, marketed by Biovitrum) is a truncated human recombinant keratinocyte growth factor (KGF)[1] produced in Escherichia coli. KGF stimulates the growth of cells that line the surface of the mouth and intestinal tract.[2]

  1. ^ Beaven AW, Shea TC (September 2007). "The effect of palifermin on chemotherapyand radiation therapy-induced mucositis: a review of the current literature". Supportive Cancer Therapy. 4 (4): 188–97. doi:10.3816/SCT.2007.n.014. PMID 18632516.
  2. ^ Kepivance entry in the public domain NCI Dictionary of Cancer Terms