Palladius may refer to:
People:
- Palladius of Antioch (died 309), also known as Palladius the Hermit, Christian saint
- Rutilius Taurus Aemilianus Palladius, 4th-century Roman agricultural writer usually known as Palladius
- Palladius of Ratiaria, late 4th-century Arian Christian theologian
- Palladius (prefect), prefect of Alexandria in 373
- Palladius of Galatia (360s–420s) also known as Palladius Helenopolitanus, the author of Historia Lausiaca
- Junius Quartus Palladius, Praetorian Prefect in the Western Roman Empire in the early 5th century
- Palladius (Caesar) (420–455), son of Western Roman Emperor Petronius Maximus, Caesar of the Western Roman Empire
- Palladius (bishop of Ireland) (fl. 408-431; died ca. 457/461), also known as Palladius the Deacon, first Bishop of the Christians of Ireland, preceding Saint Patrick
- Palladius of Embrun (died ca. 541 AD), also known as Pallade, Pélade, Patllari, bishop of Embrun
- Palladius of Saintes, or Pallais of Saintes, 6th-century bishop of Saintes in Gaul
- Palladius (physician), 6th or 7th century, author of two books of commentary on Hippocrates
- Peder Palladius (1503–1560), first Lutheran bishop of the Church of Denmark
- Palladius (Kafarov) (1817–1878), named as Archimandrite Palladius or Pyotr Kafarov, early Russian sinologist, author of the standard Russian transcription scheme for Chinese words