Pancreatic islets

Pancreatic islets
Pancreatic islets are groups of cells found within the pancreas that release hormones
A pancreatic islet from a mouse in a typical position, close to a blood vessel; insulin in red, nuclei in blue.
Details
Part ofPancreas
SystemEndocrine
Identifiers
Latininsulae pancreaticae
MeSHD007515
TA98A05.9.01.019
TA23128
FMA16016
Anatomical terms of microanatomy

The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans.[1] The pancreatic islets constitute 1–2% of the pancreas volume and receive 10–15% of its blood flow.[2][3] The pancreatic islets are arranged in density routes throughout the human pancreas, and are important in the metabolism of glucose.[4]

  1. ^ Langerhans P (1869). "Beitrage zur mikroscopischen anatomie der bauchspeichel druse". Inaugural-dissertation. Berlin: Gustav Lange.
  2. ^ Barrett KE, Boitano S, Barman SM, Brooks HL (2009-07-22). Ganong's review of medical physiology (23 ed.). McGraw Hill Medical. p. 316. ISBN 978-0-07-160568-7.
  3. ^ Functional Anatomy of the Endocrine Pancreas
  4. ^ Pour PM, Standop J, Batra SK (January 2002). "Are islet cells the gatekeepers of the pancreas?". Pancreatology. 2 (5): 440–448. doi:10.1159/000064718. PMID 12378111. S2CID 37257345.