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Paolo Brenner (born 21 May 1966, in Höchstädt an der Donau) is a German physician and a professor of cardiac surgery at the Department of Cardiac Surgery, Klinikum Großhadern of the Ludwig Maximilian University of Munich (LMU). He is known for his work in the fields of xenotransplantation, the advancement of artificial hearts, extracorporeal membrane oxygenation (ECMO) and lung transplantation.