Parathion

Parathion
Names
Preferred IUPAC name
O,O-Diethyl O-(4-nitrophenyl) phosphorothioate
Other names
E605
Identifiers
3D model (JSmol)
2059093
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.247 Edit this at Wikidata
EC Number
  • 200-271-7
KEGG
RTECS number
  • TF4550000
UNII
UN number 3018 2783
  • InChI=1S/C10H14NO5PS/c1-3-14-17(18,15-4-2)16-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3 checkY
    Key: LCCNCVORNKJIRZ-UHFFFAOYSA-N checkY
  • InChI=1/C10H14NO5PS/c1-3-14-17(18,15-4-2)16-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3
    Key: LCCNCVORNKJIRZ-UHFFFAOYAR
  • S=P(Oc1ccc(cc1)[N+]([O-])=O)(OCC)OCC
Properties
C10H14NO5PS
Molar mass 291.26 g·mol−1
Appearance White crystals (pure form)
Melting point 6 °C (43 °F; 279 K)
24 mg/L
Solubility in other solvents high solubility

in xylene and butanol

Hazards
GHS labelling:
GHS06: ToxicGHS08: Health hazardGHS09: Environmental hazard
Danger
H300, H311, H330, H372, H410
P260, P264, P270, P271, P273, P280, P284, P301+P310, P302+P352, P304+P340, P310, P312, P314, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, P501
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 4: Very short exposure could cause death or major residual injury. E.g. VX gasFlammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oilInstability 2: Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water. E.g. white phosphorusSpecial hazards (white): no code
4
1
2
Flash point 120 °C (248 °F; 393 K)
Lethal dose or concentration (LD, LC):
5 mg/kg (mouse, oral)
10 mg/kg (rabbit, oral)
3 mg/kg (dog, oral)
0.93 mg/kg (cat, oral)
5 mg/kg (horse, oral)
8 mg/kg (guinea pig, oral)
2 mg/kg (rat, oral)[3]
84 mg/m3 (rat, 4 hr)[3]
50 mg/m3 (rabbit, 2 hr)
14 mg/m3 (guinea pig, 2 hr)
15 mg/m3 (mouse)[3]
NIOSH (US health exposure limits):
PEL (Permissible)
 none (methyl parathion),[1] TWA 0.1 mg/m3 [skin] (ethyl parathion)[2]
REL (Recommended)
 TWA 0.2 mg/m3 [skin] (methyl parathion)[1] TWA 0.05 mg/m3 [skin] (ethyl parathion)[2]
IDLH (Immediate danger)
 N.D. (methyl parathion)[1] 10 mg/m3 (ethyl parathion)[2]
Safety data sheet (SDS) [1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Parathion, also called parathion-ethyl or diethyl parathion, is an organophosphate insecticide and acaricide. It was originally developed by IG Farben in the 1940s. It is highly toxic to non-target organisms, including humans, so its use has been banned or restricted in most countries. In response to safety concerns, the less toxic but still dangerous analogue parathion methyl was later developed.[5]

  1. ^ a b c NIOSH Pocket Guide to Chemical Hazards. "#0427". National Institute for Occupational Safety and Health (NIOSH).
  2. ^ a b c NIOSH Pocket Guide to Chemical Hazards. "#0479". National Institute for Occupational Safety and Health (NIOSH).
  3. ^ a b c "Parathion". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
  4. ^ "Hazard Rating Information for NFPA Fire Diamonds". Archived from the original on 2015-02-17. Retrieved 2015-03-13.
  5. ^ "Parathion". www.fao.org. Retrieved 2020-04-17.