| Pars compacta | |
|---|---|
 | |
| Details | |
| Part of | substantia nigra |
| Identifiers | |
| Latin | pars compacta substantiae nigrae |
| Acronym(s) | SNpc |
| MeSH | D065842 |
| NeuroLex ID | birnlex_990 |
| TA98 | A14.1.06.112 |
| TA2 | 5882 |
| FMA | 62907 |
| Anatomical terms of neuroanatomy | |
The pars compacta (SNpc) is one of two subdivisions of the substantia nigra of the midbrain (the other being the pars reticulata); it is situated medial to the pars reticulata. It is formed by dopaminergic neurons.[1] It projects to the striatum and portions of the cerebral cortex.[2] It is functionally involved in fine motor control.
Parkinson's disease is characterized by the death of dopaminergic neurons in this region.[1]
- ^ a b Kim, S. J.; Sung, JY; Um, JW; Hattori, N; Mizuno, Y; Tanaka, K; Paik, SR; Kim, J; Chung, KC (2003). "Parkin Cleaves Intracellular -Synuclein Inclusions via the Activation of Calpain". Journal of Biological Chemistry. 278 (43): 41890–9. doi:10.1074/jbc.M306017200. PMID 12917442.
- ^ Martin, John D. (2020). Neuroanatomy: Text and Atlas (5th ed.). New York: McGraw Hill. p. 309. ISBN 978-1-259-64248-7.