Patricia Smith may refer to:
- Patricia Smith (bowls) (1920–2017), Australian lawn bowler
- Patricia Smith (poet) (born 1955), American poet and writer
- Tricia Smith (born 1957), Canadian rower and lawyer
- Patricia Smith, Viscountess Hambleden (1904–1994), Lady of the Bedchamber to Queen Elizabeth
- Patricia Anne Smith (born 1943), former politician in Saskatchewan, Canada
- Patricia Haynes Smith (born 1946), member of the Louisiana House of Representatives
- Patricia Hornsby-Smith, Baroness Hornsby-Smith (1914–1985), British politician
- Patricia Spafford Smith (1925–2002), American businesswoman and politician
- M. Patricia Smith (born circa 1952), American labor lawyer and government official
- Patricia Smith (actress) (1930–2011), movie and television actress
- Patricia Southall (born 1971), later Smith, founder and spokesperson of Treasure You