| Clinical data | |
|---|---|
| Trade names | Palforzia |
| Other names | AR101, peanut allergen powder-dnfp, peanut (Arachis hypogaea) allergen powder-dnfp |
| AHFS/Drugs.com | Professional Drug Facts |
| License data | |
| Routes of administration | By mouth |
| ATC code |
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| Legal status | |
| Legal status | |
| Identifiers | |
| PubChem SID | |
| DrugBank | |
| UNII | |
Peanut allergen powder, sold under the brand name Palforzia, is an oral medication used for the treatment of children who have confirmed cases of peanut allergy.[2][3][4] It is taken by mouth.[2][4]
Peanut allergen powder is a powder that is manufactured from peanuts (Arachis hypogaea) and packaged in pull-apart color-coded capsules for dose escalation and up-dosing, and in a sachet for maintenance treatment.[2][6]
The most common side effects of peanut allergen powder are abdominal pain, vomiting, nausea, tingling in the mouth, itching (including in the mouth and ears), cough, runny nose, throat irritation and tightness, hives, wheezing and shortness of breath and anaphylaxis.[2][6] Peanut allergen powder should not be administered to those with uncontrolled asthma.[2][6]
In January 2020, the FDA approved the drug to Aimmune Therapeutics for mitigating "allergic reactions, including anaphylaxis, that may occur with accidental exposure to peanuts."[6][7] It is the first drug approved for treating peanut allergies.[8]
- ^ "Palforzia - Summary of Product Characteristics (SmPC)". (emc). 15 July 2021. Archived from the original on 28 May 2022. Retrieved 24 March 2022.
- ^ a b c d e f "Palforzia Initial Dose Escalation- peanut kit Palforzia (Level 1)- peanut powder Palforzia (Level 2)- peanut powder Palforzia (Level 3)- peanut kit Palforzia (Level 4)- peanut powder Palforzia (Level 5)- peanut powder Palforzia (Level 6)- peanut powder Palforzia (Level 7)- peanut kit Palforzia (Level 8)- peanut kit Palforzia (Level 9)- peanut powder Palforzia (Level 10)- peanut kit Palforzia (Level 11)- peanut powder". DailyMed. 14 February 2020. Archived from the original on 9 August 2024. Retrieved 13 August 2020.
- ^ a b "Palforzia". U.S. Food and Drug Administration (FDA). 7 February 2020. STN: 125696. Archived from the original on 13 February 2020. Retrieved 12 February 2020.
This article incorporates text from this source, which is in the public domain.
- ^ a b c "Palforzia EPAR". European Medicines Agency. 13 October 2020. Archived from the original on 18 February 2022. Retrieved 24 March 2022. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
- ^ "Palforzia Product information". Union Register of medicinal products. Archived from the original on 5 March 2023. Retrieved 3 March 2023.
- ^ a b c d "FDA approves first drug for treatment of peanut allergy for children". U.S. Food and Drug Administration (FDA) (Press release). 31 January 2020. Archived from the original on 1 February 2020. Retrieved 31 January 2020. This article incorporates text from this source, which is in the public domain.
- ^ "Palforzia Approval Letter". U.S. Food and Drug Administration (FDA). 31 January 2020. Archived from the original on 26 December 2020. Retrieved 13 February 2020.
- ^ "The FDA has approved the first drug to treat peanut allergies". Science News. 4 February 2020. Archived from the original on 9 August 2024. Retrieved 13 February 2020.
