Pennsylvania Route 641

Pennsylvania Route 641
PA 641 in red and PA 641 Truck in blue
Route information
Maintained by PennDOT
Length	57.895 mi[1] (93.173 km)
Major junctions
West end	US 522 near Shade Gap
Major intersections	PA 35 near Shade Gap PA 75 in Spring Run PA 997 in Roxbury PA 696 in Newburg PA 233 in Newville US 11 / PA 34 / PA 74 in Carlisle I-81 near Carlisle PA 174 near Mechanicsburg PA 114 in Mechanicsburg US 11 / PA 581 in Camp Hill
East end	US 11 / US 15 in Camp Hill
Location
Country	United States
State	Pennsylvania
Counties	Huntingdon, Franklin, Cumberland
Highway system
Pennsylvania State Route System Interstate US State Scenic Legislative
← PA 639 → PA 642

Pennsylvania Route 641 (PA 641) is a state route that is located in Central Pennsylvania in the United States. The route is 57.9 miles (93.2 km) long and runs from U.S. Route 522 (US 522) near Shade Gap east to US 11/US 15 in Camp Hill.

PA 641 heads east from Shade Gap in Huntingdon County and immediately crosses PA 35 before it heads across Tuscarora Mountain into Franklin County. The route intersects PA 75 in Spring Run before it crosses Kittatinny and Blue mountains and reaches a junction with PA 997 in Roxbury. PA 641 heads into the agricultural Cumberland Valley and enters Cumberland County, where it intersects PA 696 in Newburg and PA 233 in Newville before reaching Carlisle.

In Carlisle, the route runs concurrent with US 11 and PA 74 on High Street and crosses PA 34 in the center of town. East of here, PA 641 has an interchange with Interstate 81 (I-81) and heads to Mechanicsburg, where it intersects PA 114. The route continues through the western suburbs of Harrisburg and has an interchange with US 11/PA 581 before ending in Camp Hill. PA 641 has a truck route, PA 641 Truck, that bypasses the winding stretch across Kittatinny Mountain.

PA 641 was designated in 1928 to run from PA 74 in Carlisle east to US 11 (Carlisle Pike) in Camp Hill. The same year, the road between Shade Gap and east of Spring Run and for a short distance to the west of Roxbury became part of PA 433 while PA 333 was designated onto the road between Roxbury and Newburg.

In 1937, PA 641 was extended west to PA 433 east of Spring Run, replacing the portion of PA 333 between Roxbury and Newburg and running concurrent with PA 433 for a short distance to the west of Roxbury. The east end was moved to its current location at US 15 in the 1950s, with a realigned US 15 replacing the section of PA 641 north on 32nd Street to Carlisle Pike. In the 1960s, PA 641 was extended west to Shade Gap, replacing that stretch of PA 433 while the PA 433 designation was also removed from the road to the west of Roxbury.