Pennsylvania Route 646

Pennsylvania Route 646
Route information
Maintained by PennDOT
Length	19.153 mi[1] (30.824 km)
Existed	1928[2]–present
Major junctions
South end	PA 59 in Keating Township
Major intersections	PA 770 in Keating Township PA 46 in Foster Township PA 246 in Otto Township PA 346 in Foster Township
North end	NY 16 at the New York state line in Foster Township
Location
Country	United States
State	Pennsylvania
Counties	McKean
Highway system
Pennsylvania State Route System Interstate US State Scenic Legislative
← PA 645 → PA 647
← PA 743 → PA 747

Pennsylvania Route 646 (PA 646) is a 19.15 miles (30.82 km) long state highway located in McKean County in Pennsylvania. The southern terminus is at PA 59 in Keating Township. The northern terminus is the New York state line in Foster Township. The route continues as New York State Route 16 (NY 16) in Cattaugarus County.

PA 646 was assigned in the 1928 mass numbering of state routes in Pennsylvania. At that time, it consisted entirely of the PA 346–state line stretch in Foster Township. The rest of the stretch consisted of PA 59, now realigned, and PA 746, now decommissioned. PA 746 was decommissioned in 1946, and PA 59 was realigned in 1952, with PA 646 being extended onto its current alignment. The route has remained virtually unchanged since the change in 1952.