Peptide vaccine

Peptide-based synthetic vaccines (epitope vaccines) are subunit vaccines made from peptides. The peptides mimic the epitopes of the antigen that triggers direct or potent immune responses.[1] Peptide vaccines can not only induce protection against infectious pathogens and non-infectious diseases but also be utilized as therapeutic cancer vaccines, where peptides from tumor-associated antigens are used to induce an effective anti-tumor T-cell response.[2]

  1. ^ Skwarczynski M, Toth I (February 2016). "Peptide-based synthetic vaccines". Chemical Science. 7 (2): 842–854. doi:10.1039/C5SC03892H. PMC 5529997. PMID 28791117.
  2. ^ Melief CJ, van der Burg SH (May 2008). "Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines". Nature Reviews. Cancer. 8 (5): 351–360. doi:10.1038/nrc2373. PMID 18418403. S2CID 205468352.