Perilipin-1

PLIN1
Identifiers
Aliases	PLIN1, FPLD4, PERI, PLIN, perilipin 1
External IDs	OMIM: 170290; MGI: 1890505; HomoloGene: 2001; GeneCards: PLIN1; OMA:PLIN1 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q26.1 Start 89,664,367 bp[1] End 89,679,427 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 D2 Start 79,369,966 bp[2] End 79,382,651 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in subcutaneous adipose tissue abdominal fat skin of hip lactiferous duct synovial joint pericardium parotid gland Skeletal muscle tissue of rectus abdominis right lobe of liver synovial membrane Top expressed in white adipose tissue brown adipose tissue mammary gland subcutaneous adipose tissue intercostal muscle sciatic nerve mesenteric lymph nodes ankle skin of abdomen parotid gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function lipid binding Cellular component lipid droplet endoplasmic reticulum cytosol Biological process lipid metabolism lipid catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5346 103968 Ensembl ENSG00000166819 ENSMUSG00000030546 UniProt O60240 Q8CGN5 RefSeq (mRNA) NM_001145311 NM_002666 NM_001113471 NM_175640 RefSeq (protein) NP_001138783 NP_002657 NP_001106942 NP_783571 Location (UCSC) Chr 15: 89.66 – 89.68 Mb Chr 7: 79.37 – 79.38 Mb PubMed search [3] [4]
Wikidata
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Perilipin, also known as lipid droplet-associated protein, perilipin 1, or PLIN, is a protein that, in humans, is encoded by the PLIN gene.^[5] The perilipins are a family of proteins that associate with the surface of lipid droplets. Phosphorylation of perilipin is essential for the mobilization of fats in adipose tissue.^[6]