Period (gene)

per
Identifiers
OrganismD. melanogaster
Symbolper
Entrez31251
RefSeq (mRNA)NM_080317
RefSeq (Prot)NP_525056
UniProtP07663
Other data
ChromosomeX: 2.58 - 2.59 Mb
Search for
StructuresSwiss-model
DomainsInterPro

Period (per) is a gene located on the X chromosome of Drosophila melanogaster. Oscillations in levels of both per transcript and its corresponding protein PER have a period of approximately 24 hours and together play a central role in the molecular mechanism of the Drosophila biological clock driving circadian rhythms in eclosion and locomotor activity.[1][2] Mutations in the per gene can shorten (perS), lengthen (perL), and even abolish (per0) the period of the circadian rhythm.[1]

  1. ^ a b Cite error: The named reference PERcycle was invoked but never defined (see the help page).
  2. ^ Dunlap, JC (January 1999). "Molecular Bases for Circadian Clocks". Cell. 96 (2): 271–290. doi:10.1016/S0092-8674(00)80566-8. PMID 9988221. S2CID 14991100.