Peroxisome proliferator-activated receptor delta

PPARD
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB, peroxisome proliferator activated receptor delta
External IDsOMIM: 600409; MGI: 101884; HomoloGene: 4544; GeneCards: PPARD; OMA:PPARD - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001171818
NM_001171819
NM_001171820
NM_006238
NM_177435

NM_011145

RefSeq (protein)

NP_001165289
NP_001165290
NP_001165291
NP_006229
NP_803184

NP_035275

Location (UCSC)Chr 6: 35.34 – 35.43 MbChr 17: 28.23 – 28.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene.[5]

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993.[6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000112033Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000002250Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Schmidt A, Endo N, Rutledge SJ, Vogel R, Shinar D, Rodan GA (October 1992). "Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids". Molecular Endocrinology. 6 (10): 1634–1641. doi:10.1210/mend.6.10.1333051. PMID 1333051. S2CID 23506853.
  6. ^ Krey G, Keller H, Mahfoudi A, Medin J, Ozato K, Dreyer C, et al. (December 1993). "Xenopus peroxisome proliferator activated receptors: genomic organization, response element recognition, heterodimer formation with retinoid X receptor and activation by fatty acids". The Journal of Steroid Biochemistry and Molecular Biology. 47 (1–6): 65–73. doi:10.1016/0960-0760(93)90058-5. PMID 8274443. S2CID 25098754.