Phendimetrazine

"Mephenmetrazine" redirects here. For other methyl substitutions of phenmetrazine, see Phenmetrazine § Substituted phenmetrazines.

Phendimetrazine
Clinical data
Trade namesBontril
AHFS/Drugs.comMonograph
Routes of
administration		By mouth
ATC code
  • none
Legal status
Legal status
Pharmacokinetic data
BioavailabilityPeak plasma levels occur within 1 to 3 hours. Absorption is usually complete by 4 to 6 hours
MetabolismLiver
Elimination half-life19-24 hours
ExcretionUrinary elimination
Identifiers
  • 3,4-dimethyl-2-phenylmorpholine
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.010.186 Edit this at Wikidata
Chemical and physical data
FormulaC12H17NO
Molar mass191.274 g·mol−1
3D model (JSmol)
  • C[C@H]1[C@@H](OCCN1C)C2=CC=CC=C2
  • InChI=1S/C12H17NO/c1-10-12(14-9-8-13(10)2)11-6-4-3-5-7-11/h3-7,10,12H,8-9H2,1-2H3/t10-,12+/m0/s1 checkY
  • Key:MFOCDFTXLCYLKU-CMPLNLGQSA-N checkY
  (verify)

Phendimetrazine, sold under the brand name Bontril among others, is a stimulant medication of the morpholine chemical class used as an appetite suppressant.[2]

  1. ^ Anvisa (31 March 2023). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 4 April 2023). Archived from the original on 3 August 2023. Retrieved 16 August 2023.
  2. ^ Landau D, Jackson J, Gonzalez G (2008). "A case of demand ischemia from phendimetrazine". Cases J. 1 (1): 105. doi:10.1186/1757-1626-1-105. PMC 2531092. PMID 18710555.