Phenylbutazone

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Phenylbutazone

Clinical data
Trade names	Butazolidine
ATC code	M01AA01 (WHO) M02AA01 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 4-Butyl-1,2-diphenyl-pyrazolidine-3,5-dione
CAS Number	50-33-9 Y
PubChem CID	4781
IUPHAR/BPS	7270
DrugBank	DB00812 Y
ChemSpider	4617 Y
UNII	GN5P7K3T8S
KEGG	D00510 Y
ChEBI	CHEBI:48574 Y
ChEMBL	ChEMBL101 Y
CompTox Dashboard (EPA)	DTXSID9021136
ECHA InfoCard	100.000.027
Chemical and physical data
Formula	C19H20N2O2
Molar mass	308.381 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C2N(c1ccccc1)N(C(=O)C2CCCC)c3ccccc3
InChI InChI=1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3 Y Key:VYMDGNCVAMGZFE-UHFFFAOYSA-N Y
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Phenylbutazone, often referred to as "bute",^[1] is a nonsteroidal anti-inflammatory drug (NSAID) for the short-term treatment of pain and fever in animals.

In the United States and United Kingdom, it is no longer approved for human use (except in the United Kingdom for ankylosing spondylitis), as it can cause severe adverse effects such as suppression of white blood cell production and aplastic anemia. This drug was implicated in the 2013 meat adulteration scandal. Positive phenylbutazone tests in horse meat were uncommon in the UK, however.^[2]