Phenylethanolamine N-methyltransferase

phenylethanolamine N-methyltransferase
Phenylethanolamine N-methyltransferase monomer, Human
Identifiers
SymbolPNMT
Alt. symbolsPENT
NCBI gene5409
HGNC9160
OMIM171190
RefSeqNM_002686
UniProtP11086
Other data
EC number2.1.1.28
LocusChr. 17 q21-q22
Search for
StructuresSwiss-model
DomainsInterPro

Phenylethanolamine N-methyltransferase (PNMT) is an enzyme found primarily in the adrenal medulla that converts norepinephrine (noradrenaline) to epinephrine (adrenaline).[1] It is also expressed in small groups of neurons in the human brain[2] and in selected populations of cardiomyocytes.[3]

  1. ^ Cite error: The named reference Medulla PNMT was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference Human PNMT neurons was invoked but never defined (see the help page).
  3. ^ Wang Y, Lin WK, Crawford W, Ni H, Bolton EL, Khan H, et al. (January 2017). "+ Cells in Murine Heart". Scientific Reports. 7 (1): 40687. doi:10.1038/srep40687. PMC 5234027. PMID 28084430.