Physiomics

Physiomics is a systematic study of physiome in biology. Physiomics employs bioinformatics to construct networks of physiological features that are associated with genes, proteins and their networks. A few of the methods for determining individual relationships between the DNA sequence and physiological function include metabolic pathway engineering[1] and RNAi analysis.[2] The relationships derived from methods such as these are organized and processed computationally to form distinct networks. Computer models use these experimentally determined networks to develop further predictions of gene function.[3][4]

  1. ^ Bailey, J.E (1991). "Toward a science of metabolic engineering". Science. 252 (5013): 1668–1675. doi:10.1126/science.2047876. PMID 2047876.
  2. ^ Kamath, Ravi S.; Fraser, Andrew G.; Dong, Yan; Poulin, Gino; Durbin, Richard; Gotta, Monica; Kanapin, Alexander (2003). "Systematic functional analysis of the Caenorhabditis elegans genome using RNAi". Nature. 421 (6920): 231–237. doi:10.1038/nature01278. hdl:10261/63159. PMID 12529635.
  3. ^ Cite error: The named reference :0 was invoked but never defined (see the help page).
  4. ^ Sanford, Karl; Soucaille, Phillipe; Whited, Gregg; Chotani, Gopal (2002). "Genomics to fluxomics and physiomics — pathway engineering". Current Opinion in Microbiology. 5 (3): 318–322. doi:10.1016/S1369-5274(02)00318-1.