Piecemeal necrosis

Sclerotic piecemeal necrosis of the tip of the thumb in a patient with scleroderma.

Piecemeal necrosis generally refers to a necrosis that occurs in fragments.

Piecemeal necrosis in liver aka interface hepatitis is necrosis of the limiting plates, by inflammatory cells. It may be identified as actual necrosis of cells or by irregularity of the limiting plates which is caused IOS's hepatocytes and replacement with inflammatory cells and/or fibrosis.