Porphyromonas

Porphyromonas
Colonies of Porphyromonas gulae growing on a TSA plate
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Bacteroidota
Class: Bacteroidia
Order: Bacteroidales
Family: Porphyromonadaceae
Genus: Porphyromonas
Shah and Collins 1988[1]
Type species
Porphyromonas asaccharolytica[1]
Species

P. asaccharolytica[1]
P. bennonis[1]
P. cangingivalis[1]
P. canoris[1]
P. catoniae[1]
P. circumdentaria[1]
P. crevioricanis[1]
P. endodontalis[1]
P. gingivalis[1]
P. gingivicanis[1]
P. gulae[1]
P. levii[1]
P. macacae[1]
P. pasteri[1]
P. pogonae[1]
P. somerae[1]
P. uenonis[1]

Synonyms[2]
  • Oribaculum Moore and Moore 1994

Porphyromonas is a Gram-negative, non-spore-forming, obligately anaerobic and non-motile genus from the family Porphyromonadaceae.[3][1][2][4] There were 16 different Porphyromonas species documented as of 2015, which reside in both animal and human reservoirs.[5] It was discovered more recently that Porphyromonas also exist in the environment, albeit to a lesser extent.[6] This genus is notably implicated in the modulation of oral cavity, respiratory tract, and gastrointestinal tract disease states.[5] It is suggested that Porphyromonas either operate as benign bacteria pertinent to host immunity or are potential pathobionts that opportunistically provoke diseased states when homeostasis is disrupted.[6] Despite its characterization not being fully elucidated due to sparse research, various studies report the prevalence of this genus at 58.7% in healthy states compared with 41.3% in diseased states.[6]

This genus was first reported in the oral cavity[5] and is found specifically in the salivary microbiome.[7] Porphyromonas are also commonly found in the microbiome of the human digestive tract, as shown by the Human Microbiome Project in general.[8]

  1. ^ a b c d e f g h i j k l m n o p q r s t Parte, A.C. "Porphyromonas". LPSN.
  2. ^ a b "Porphyromonas". www.uniprot.org.
  3. ^ Summanen, Paula; Finegold, Sydney M. (1 January 2015). "Porphyromonas". Bergey's Manual of Systematics of Archaea and Bacteria. John Wiley & Sons, Ltd: 1–14. doi:10.1002/9781118960608.gbm00246. ISBN 9781118960608.
  4. ^ Parker, Charles Thomas; Wigley, Sarah; Garrity, George M (2009). Parker, Charles Thomas; Garrity, George M (eds.). "Nomenclature Abstract for Porphyromonas". The NamesforLife Abstracts. doi:10.1601/nm.8020 (inactive 1 November 2024).{{cite journal}}: CS1 maint: DOI inactive as of November 2024 (link)
  5. ^ a b c Guilloux, Charles-Antoine; Lamoureux, Claudie; Beauruelle, Clémence; Héry-Arnaud, Geneviève (April 2021). "Porphyromonas: A neglected potential key genus in human microbiomes". Anaerobe. 68: 102230. doi:10.1016/j.anaerobe.2020.102230. ISSN 1075-9964. PMID 32615270. S2CID 220329292.
  6. ^ a b c Acuña-Amador, Luis; Barloy-Hubler, Frédérique (December 2020). "Porphyromonas spp. have an extensive host range in ill and healthy individuals and an unexpected environmental distribution: A systematic review and meta-analysis". Anaerobe. 66: 102280. doi:10.1016/j.anaerobe.2020.102280. hdl:10669/81718. ISSN 1075-9964. PMID 33011277. S2CID 222169436.
  7. ^ Wang, Kun; Lu, Wenxin; Tu, Qichao; Ge, Yichen; He, Jinzhi; Zhou, Yu; Gou, Yaping; Nostrand, Joy D Van; Qin, Yujia; Li, Jiyao; Zhou, Jizhong; Li, Yan; Xiao, Liying; Zhou, Xuedong (10 March 2016). "Preliminary analysis of salivary microbiome and their potential roles in oral lichen planus". Scientific Reports. 6 (1): 22943. Bibcode:2016NatSR...622943W. doi:10.1038/srep22943. PMC 4785528. PMID 26961389.
  8. ^ The Human Microbiome Project Consortium (June 2012). "Structure, function and diversity of the healthy human microbiome". Nature. 486 (7402): 207–214. Bibcode:2012Natur.486..207T. doi:10.1038/nature11234. ISSN 0028-0836. PMC 3564958. PMID 22699609.