| Powassan encephalitis | |
|---|---|
| Specialty | Infectious diseases  |
Powassan encephalitis, caused by the Powassan virus (POWV), a flavivirus also known as the deer tick virus, is a form of arbovirus infection that results from tick bites. It can occur as a co-infection with Lyme disease, as both are transmitted to humans by the same species of tick.[1] Over the last decade, there has been a surge in the number of cases and an expansion of its geographic range. In the United States, cases have been documented primarily in the northeast.[2] The disease was first isolated from the brain of a boy who died of encephalitis in Powassan, Ontario, in 1958.[3] This disease is classified as a zoonosis, originating in animals, often found in rodents and ticks, with subsequent transmission to humans. The virus shares antigenic similarities with the Far Eastern tick-borne encephalitis viruses.[4]
- ^ Caulfield AJ, Pritt BS (December 2015). "Lyme Disease Coinfections in the United States". Clinics in Laboratory Medicine. 35 (4): 827–46. doi:10.1016/j.cll.2015.07.006. PMID 26593260.
- ^ "Cumulative human disease cases reported to CDC ArboNET for 2015". United States Geological Survey. Archived from the original on 2016-12-15. Retrieved 2015-11-27.
- ^ McLEAN DM, DONOHUE WL (1 May 1959). "Powassan virus: isolation of virus from a fatal case of encephalitis". Canadian Medical Association Journal. 80 (9): 708–11. PMC 1830849. PMID 13652010.
- ^ CASALS J (13 February 1960). "Antigenic relationship between Powassan and Russian spring-summer encephalitis viruses". Canadian Medical Association Journal. 82 (7): 355–8. PMC 1937779. PMID 13808112.