Premazepam

Premazepam
Pharmacokinetic data
Metabolism	Hepatic
Elimination half-life	10–13 hours
Excretion	Renal
Identifiers
	IUPAC name 6,7-Dimethyl-5-phenyl-1,3-dihydropyrrolo[3,4-e][1,4]diazepin-2-one;
CAS Number	57435-86-6 ;
PubChem CID	72104;
ChemSpider	65088 ;
UNII	OI7443PDLB;
ChEMBL	ChEMBL2104741 ;
CompTox Dashboard (EPA)	DTXSID60206026 ;
Chemical and physical data
Formula	C15H15N3O
Molar mass	253.305 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Cc1c2c(cn1C)NC(=O)CN=C2c3ccccc3;
	InChI InChI=1S/C15H15N3O/c1-10-14-12(9-18(10)2)17-13(19)8-16-15(14)11-6-4-3-5-7-11/h3-7,9H,8H2,1-2H3,(H,17,19) ; Key:CNWSHOJSFGGNLC-UHFFFAOYSA-N ;
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Premazepam is a Pyrrolodiazepine class of drug. ^[1] It is a partial agonist of benzodiazepine receptors and was shown in 1984 to possess both anxiolytic and sedative properties in humans but was never marketed.

^ Assandri A, Barone D, Ferrari P, Perazzi A, Ripamonti A, Tuan G, Zerilli LF (Mar–Apr 1984). "Metabolic fate of premazepam, a new anti-anxiety drug, in the rat and the dog". Drug Metabolism and Disposition. 12 (2): 257–63. PMID 6144494.

[1] Assandri A, Barone D, Ferrari P, Perazzi A, Ripamonti A, Tuan G, Zerilli LF (Mar–Apr 1984). "Metabolic fate of premazepam, a new anti-anxiety drug, in the rat and the dog". Drug Metabolism and Disposition. 12 (2): 257–63. PMID 6144494.

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