Primase

Toprim domain
Identifiers
SymbolToprim
PfamPF01751
Pfam clanToprim-like
InterProIPR006171
SCOP22fcj / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Toprim catalytic core
Identifiers
SymbolToprim_N
PfamPF08275
InterProIPR013264
SCOP21dd9 / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
AEP DNA primase, small subunit
Identifiers
SymbolDNA_primase_S
PfamPF01896
Pfam clanAEP
InterProIPR002755
SCOP21g71 / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
AEP DNA primase, large subunit
Identifiers
SymbolDNA_primase_lrg
PfamPF04104
Pfam clanCL0242
InterProIPR007238
SCOP21zt2 / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

DNA primase is an enzyme involved in the replication of DNA and is a type of RNA polymerase. Primase catalyzes the synthesis of a short RNA (or DNA in some living organisms[1]) segment called a primer complementary to a ssDNA (single-stranded DNA) template. After this elongation, the RNA piece is removed by a 5' to 3' exonuclease and refilled with DNA.

  1. ^ Bocquier AA, Liu L, Cann IK, Komori K, Kohda D, Ishino Y (March 2001). "Archaeal primase: bridging the gap between RNA and DNA polymerases". Current Biology. 11 (6): 452–6. doi:10.1016/s0960-9822(01)00119-1. PMID 11301257.