Princess Sophie of Saxe-Weimar-Eisenach may refer to:
- Princess Sophie of the Netherlands (1824–1897), wife of Charles Alexander, Grand Duke of Saxe-Weimar-Eisenach
- Princess Sophie of Saxe-Weimar-Eisenach (1888–1913), daughter of Prince William of Saxe-Weimar-Eisenach (noteworthy for her suicide)
- Princess Sophie of Saxe-Weimar-Eisenach (1911–1988), daughter of William Ernest, Grand Duke of Saxe-Weimar-Eisenach
This disambiguation page lists articles associated with the title Princess Sophie of Saxe-Weimar-Eisenach.
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