Priscus is the Latin word for "ancient" or "venerable." There were several figures in Antiquity named Priscus:
- Priscus of Panium, 5th-century historian
- Priscus Attalus, senator and briefly Emperor
- Priscus of Epirus, 4th-century Neoplatonist philosopher and friend of the emperor Julian
- Marcus Statius Priscus, 2nd-century Roman general and politician
- Caerellius Priscus, governor of Roman Britain in the 170s
- Gaius Julius Priscus, Roman usurper
- Priscus (magister militum), Byzantine general of the late 6th/early 7th centuries
- Helvidius Priscus, Stoic philosopher
- Tarquinius Priscus, legendary king of Rome
- Clutorius Priscus, Roman poet
- Priscus (gladiator), 1st-century Roman gladiator
- Saint Priscus
- Iavolenus Priscus, 1st-century Roman jurist
- Titus Julius Priscus, 3rd-century Roman governor and usurper
- Priscus of Lyon (d. in the 580s), bishop of Lyon