Prodiginines

Serratia marcescens growing on bread, showing characteristic colour of the prodiginines

The prodiginines are a family of red tripyrrole dyestuffs produced by Gammaproteobacteria (e.g. Serratia marcescens) as well as some Actinomycetota (e.g. Streptomyces coelicolor). The group is named after prodigiosin (prodiginine) and is biosynthesized through a common set of enzymes.[1] They are interesting due to their history and their varied biological activity.[2]

  1. ^ Sakai-Kawada, Francis E.; Ip, Courtney G.; Hagiwara, Kehau A.; Awaya, Jonathan D. (2019). "Biosynthesis and Bioactivity of Prodiginine Analogs in Marine Bacteria, Pseudoalteromonas: A Mini Review". Frontiers in Microbiology. 10: 1715. doi:10.3389/fmicb.2019.01715. PMC 6667630. PMID 31396200.
  2. ^ Williamson NR, Fineran PC, Gristwood T, Leeper FJ, Salmond GP (2006). "The biosynthesis and regulation of bacterial prodiginines". Nature Reviews Microbiology. 4 (12): 887–899. doi:10.1038/nrmicro1531. PMID 17109029. S2CID 11649828.