Prokinetic agent

A prokinetic agent (also prokineticin, gastroprokinetic agent, gastrokinetic agent or propulsive) is a type of drug which enhances gastrointestinal motility by increasing the frequency or strength of contractions, but without disrupting their rhythm.[1] They are used to treat certain gastrointestinal symptoms, including abdominal discomfort, bloating, constipation, heart burn, nausea, and vomiting; and certain gastrointestinal disorders, including irritable bowel syndrome, gastritis,[2] gastroparesis, and functional dyspepsia.

Most prokinetic agents are grouped under the Anatomical Therapeutic Chemical Classification System (a World Health Organization drug classification system), as ATC code A03F.

  1. ^ Vincenzi M, Kremić A, Jouve A, Lattanzi R, Miele R, Benharouga M, Alfaidy N, Migrenne-Li S, Kanthasamy AG, Porcionatto M, Ferrara N, Tetko IV, Désaubry L, Nebigil CG (November 2023). Touyz R (ed.). "Therapeutic Potential of Targeting Prokineticin Receptors in Diseases". Pharmacological Reviews. 75 (6): 1167–1199. doi:10.1124/pharmrev.122.000801. ISSN 0031-6997. PMC 10595023. PMID 37684054.
  2. ^ "Acid Reflux Symptoms". Archived from the original on 2011-06-15. Retrieved 2011-06-23.