Propazepine

Not to be confused with Prazepam.
Not to be confused with Imipramine.
Propazepine
Names
Preferred IUPAC name
3-(6,11-Dihydro-5H-dibenzo[b,e]azepin-5-yl)-N,N-dimethylpropan-1-amine
Other names
Prazepine, Proazepine
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • CN(C)CCCN1CC2=CC=CC=C2CC3=CC=CC=C31
Properties
C19H24N2
Molar mass 280.415 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Propazepine is a tricyclic antidepressant (TCA).[1] Propazepine is sometimes confused with imipramine, which has the central ring nitrogen in a different location.[1] Prazepine is the International nonproprietary name of this compound.[2] Prazepine is also reported to be one of the many synonyms of imipramine.[3] Propazepine can be synthesized chemically.[4][5] Propazepine appears to never have actually been used as a tricyclic antidepressant outside of initial medical tests;[citation needed] therefore, there is little information about it.

  1. ^ a b Benešová, O.; Bohdanecký, Z.; Votava, Z. (1962). "Electrophysiological comparison of the action of imipramine and propazepine". Psychopharmacologia. 3 (6): 423–431. doi:10.1007/BF00411159. PMID 13967414. S2CID 1109255.
  2. ^ "Propazepine – C19H24N2". Pubchem.
  3. ^ "Imipramine – C19H24N2". ChemSpider.
  4. ^ Werner, L. H.; Ricca, S.; Mohacsi, E.; Rossi, A.; Arya, V. P. (1965). "Derivatives of Morphanthridine". Journal of Medicinal Chemistry. 8: 74–80. doi:10.1021/jm00325a016. PMID 14287270.
  5. ^ Jílek, J. O.; Pomykáček, J.; Svátek, E.; Seidlová, V.; Rajšner, M.; Pelz, K.; Hoch, B.; Protiva, M. (1965). "Neurotrope und psychotrope substanzen II. Morphanthridin und derivate. Neue synthese des propazepins" [Neurotropic and psychotropic substances II. Morphanthridin and derivatives. New Synthesis of propazepins]. Collection of Czechoslovak Chemical Communications (in Czech). 30 (2): 445–462. doi:10.1135/cccc19650445.