Propyphenazone

Propyphenazone
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
Identifiers
  • 1,5-Dimethyl-2-phenyl-4-propan-2-yl-pyrazol-3-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.855 Edit this at Wikidata
Chemical and physical data
FormulaC14H18N2O
Molar mass230.311 g·mol−1
3D model (JSmol)
  • O=C1C(C(C)C)=C(C)N(C)N1c2ccccc2
  • InChI=1S/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3 checkY
  • Key:PXWLVJLKJGVOKE-UHFFFAOYSA-N checkY
Saridon (Combination drug with Propyphenazone) from Hoffman-La Roche, ca. 1950/60

Propyphenazone (known as isopropylantipyrine in Japan)[1] is a derivative of phenazone[2] with similar analgesic and antipyretic effects. Originally patented in 1931,[3] propyphenazone is marketed as a combination formulation with paracetamol and caffeine for treatment of primary headache disorder.[4]

  1. ^ "Isopropylantipyrine". Drugs.com. Retrieved 8 March 2018.
  2. ^ Göres E, Kossowicz J, Schneider HG (March 2004). "[Propyphenazone. Pharmacology and use]" [Propyphenazone. Pharmacology and use]. Medizinische Monatsschrift für Pharmazeuten (in German). 27 (3): 72–6. PMID 15032249.
  3. ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 530. ISBN 9783527607495.
  4. ^ "SC exempts painkiller Saridon from the banned list in India". The Economic Times. February 21, 2019.