Prostaglandin D2 receptor

The prostaglandin D₂ (PGD₂) receptors are G protein-coupled receptors that bind and are activated by prostaglandin D₂.^[1]^[2] Also known as PTGDR or DP receptors, they are important for various functions of the nervous system and inflammation. They include the following proteins:

Prostaglandin D₂ receptor 1 (DP₁) - PTGDR1
Prostaglandin D₂ receptor 2 (DP₂) - PTGDR2

^ Domingo C, Palomares O, Sandham DA, Erpenbeck VJ, Altman P (September 2018). "The prostaglandin D₂ receptor 2 pathway in asthma: a key player in airway inflammation". Respiratory Research. 19 (1): 189. doi:10.1186/s12931-018-0893-x. PMC 6162887. PMID 30268119.
^ Brightling C, Kulkarni S, Lambrecht BN, Sandham D, Weiss M, Altman P (June 2021). "The pharmacology of the prostaglandin D₂ receptor 2 (DP₂) receptor antagonist, fevipiprant". Pulmonary Pharmacology & Therapeutics. 68: 102030. doi:10.1016/j.pupt.2021.102030. PMID 33826946. S2CID 233184866.

[Domingo_2018-1] Domingo C, Palomares O, Sandham DA, Erpenbeck VJ, Altman P (September 2018). "The prostaglandin D₂ receptor 2 pathway in asthma: a key player in airway inflammation". Respiratory Research. 19 (1): 189. doi:10.1186/s12931-018-0893-x. PMC 6162887. PMID 30268119.

[Brightling_2021-2] Brightling C, Kulkarni S, Lambrecht BN, Sandham D, Weiss M, Altman P (June 2021). "The pharmacology of the prostaglandin D₂ receptor 2 (DP₂) receptor antagonist, fevipiprant". Pulmonary Pharmacology & Therapeutics. 68: 102030. doi:10.1016/j.pupt.2021.102030. PMID 33826946. S2CID 233184866.

[1]

[2]