Prostaglandin EP3 receptor

PTGER3
Identifiers
AliasesPTGER3, EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, PGE2-R, EP3-VI, Prostaglandin E receptor 3, lnc003875
External IDsOMIM: 176806; MGI: 97795; HomoloGene: 105703; GeneCards: PTGER3; OMA:PTGER3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_011196
NM_001359745

RefSeq (protein)

n/a

Location (UCSC)Chr 1: 70.85 – 71.05 MbChr 3: 157.27 – 157.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Prostaglandin EP3 receptor (EP3, 53kDa), is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER3;[5] it is one of four identified EP receptors, the others being EP1, EP2, and EP4, all of which bind with and mediate cellular responses to PGE2 and also, but generally with lesser affinity and responsiveness, certain other prostanoids (see Prostaglandin receptors).[6] EP has been implicated in various physiological and pathological responses.[7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000050628Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040016Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "PTGER3 prostaglandin e receptor 3 [Homo sapiens (human)] - Gene - NCBI".
  6. ^ "Entrez Gene: PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa".
  7. ^ Woodward DF, Jones RL, Narumiya S (September 2011). "International Union of Basic and Clinical Pharmacology. LXXXIII: classification of prostanoid receptors, updating 15 years of progress". Pharmacological Reviews. 63 (3): 471–538. doi:10.1124/pr.110.003517. PMID 21752876.