Prostaglandin F receptor

PTGFR
Identifiers
Aliases	PTGFR, FP, Prostaglandin F receptor
External IDs	OMIM: 600563; MGI: 97796; HomoloGene: 741; GeneCards: PTGFR; OMA:PTGFR - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p31.1 Start 78,303,884 bp[1] End 78,540,701 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3 H3|3 76.96 cM Start 151,502,139 bp[2] End 151,543,267 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon gastric mucosa tibial nerve bronchial epithelial cell synovial joint smooth muscle tissue stromal cell of endometrium urethra skin of hip testicle Top expressed in lumbar spinal ganglion lower jaw incisor Meckel's cartilage mandibular molars right kidney aortic valve conjunctival fornix urethra female urethra More reference expression data BioGPS More reference expression data
Gene ontology Molecular function prostaglandin F receptor activity G protein-coupled receptor activity signal transducer activity Cellular component cytoplasm integral component of membrane extracellular region plasma membrane integral component of plasma membrane membrane Biological process G protein-coupled receptor signaling pathway response to lipopolysaccharide positive regulation of gene expression response to estradiol negative regulation of apoptotic process cellular response to prostaglandin D stimulus calcium-mediated signaling using intracellular calcium source birth positive regulation of cell population proliferation signal transduction inflammatory response adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5737 19220 Ensembl ENSG00000122420 ENSMUSG00000028036 UniProt P43088 P43117 RefSeq (mRNA) NM_000959 NM_001039585 NM_008966 RefSeq (protein) NP_000950 NP_001034674 NP_032992 Location (UCSC) Chr 1: 78.3 – 78.54 Mb Chr 3: 151.5 – 151.54 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Prostaglandin F receptor (FP) is a receptor belonging to the prostaglandin (PG) group of receptors. FP binds to and mediates the biological actions of prostaglandin F_2α (PGF_2α). It is encoded in humans by the PTGFR gene.^[5]