Prosulfocarb

Prosulfocarb[1][2]
Names
IUPAC name
S-Benzyl N,N-dipropylcarbamothioate
Other names
Prosulfocarb, A8545C
Identifiers
ECHA InfoCard 100.100.363 Edit this at Wikidata
Properties
C14H21NOS
Molar mass 251.39 g·mol−1
Appearance Colourless - pale yellow
Odor Aromatic
Density 1049 kg/m3[1]
Melting point -20 °C[3]
Boiling point 341 °C[3]
Insoluble[3]
Solubility in xylene Soluble[3]
Solubility in acetone Soluble[3]
Solubility in heptane Soluble[3]
Solubility in ethyl acetate Soluble[3]
Vapor pressure 0.79 mPa[3]
Hazards
GHS labelling:
GHS08: Health hazardGHS09: Environmental hazard
Warning
H227, H302, H317, H335, H371, H373, H401
Flash point 167.1 °C[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Prosulfocarb is a pre-emergent herbicide used agriculturally in Australia, the EU, Japan, New Zealand, (since 2020), Morocco and Iran, for control of annual ryegrass and toad rush in wheat and barley crops.[4][5][6][3] It was introduced to the EU in 1988 and is rapidly growing in use, with sales increasing by over 500% in France since 2008.[7]

Prosulfocarb is a thiocarbamate, and is absorbed by the roots of germinating seedlings to inhibit growth in the meristem by inhibiting fat synthesis,[4] of resistance HRAC Group J, (Aus),[4] K3/N, (Global), 15. (numeric)[8] Applying prosulfocarb repeatedly builds weed resistance but undoes trifluralin (Group 3) resistance, as they have opposing mechanisms: prosulfocarb is resisted by decreasing pesticide metabolism; trifluralin is resisted by increasing metabolism.[9]

  1. ^ a b c "Prosulfocarb SDS" (PDF). ChemicalBook. Retrieved 5 August 2024.
  2. ^ "Prosulfocarb Standard SDS" (PDF). FujiFilm. Retrieved 5 August 2024.
  3. ^ a b c d e f g h i Cite error: The named reference database was invoked but never defined (see the help page).
  4. ^ a b c "4Farmers Australia Prosulfocarb Leaflet" (PDF). www.4farmers.com.au. 4Farmers Australia. Retrieved 5 August 2024.
  5. ^ "Prosulfocarb 800 Label" (PDF). GenFarm. Retrieved 5 August 2024.
  6. ^ "Permission granted for new potato protector". www.epa.govt.nz. 10 August 2020.
  7. ^ Devault, Damnien; Guillemin, Jean-Philippe; Maurice, Millet; Eymery, Frank (January 2022). "Prosulfocarb at center stage!". Environmental Science and Pollution Research. doi:10.1007/s11356-019-06928-8. Retrieved 5 August 2024.
  8. ^ "2024 HRAC Global Herbicide MOA Classification Master List". Herbicide Resistance Action Committee.
  9. ^ Busi, Roberto; Goggin, Danica E; Onofri, Andrea; Boutsalis, Peter; Preston, Christopher; Powles, Stephen B; Beckie, Hugh J (December 2020). "Loss of trifluralin metabolic resistance in Lolium rigidum plants exposed to prosulfocarb recurrent selection". Pest Management Science. 76 (12): 3926–3934. doi:10.1002/ps.5993.