| Pseudoexfoliation syndrome | |
|---|---|
| Other names | Pseudoexfoliation of the lens, exfoliation syndrome |
| Specialty | Ophthalmology  |
Pseudoexfoliation syndrome, often abbreviated as PEX[1] and sometimes as PES or PXS, is an aging-related systemic disease manifesting itself primarily in the eyes which is characterized by the accumulation of microscopic granular amyloid-like protein fibers.[2] Its cause is unknown, although there is speculation that there may be a genetic basis. It is more prevalent in women than men, and in persons past the age of seventy. Its prevalence in different human populations varies; for example, it is prevalent in Scandinavia.[2] The buildup of protein clumps can block normal drainage of the eye fluid called the aqueous humor and can cause, in turn, a buildup of pressure leading to glaucoma and loss of vision[3] (pseudoexfoliation glaucoma, exfoliation glaucoma). As worldwide populations become older because of shifts in demography, PEX may become a matter of greater concern.[4]
- ^ "Glaucoma In-Depth Report". The New York Times. July 9, 2011. Retrieved July 9, 2011.
Pseudoexfoliation (PEX) syndrome ... The substance is composed of proteins produced by the lens, iris, and other parts of the eye. People can have this condition and not develop glaucoma, but they are at high risk.
- ^ a b Yichieh Shiuey, MD (March 26, 1997). "Glaucoma Quiz 1". Digital Journal of Ophthalmology. Retrieved August 21, 2011.
... In Scandinavia, this condition represents greater than 50% of all cases of open angle glaucoma.
- ^ "Glaucoma". The New York Times. August 19, 2011. Retrieved August 19, 2011.
... Pseudoexfoliation (PEX) syndrome (also known as exfoliation syndrome) is the most common identifiable condition associated with glaucoma. The substance is composed of proteins produced by the lens, iris, and other parts of the eye.
- ^ Cite error: The named reference
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