Pseudorabies

Not to be confused with rabies or rabies virus.
Suid alphaherpesvirus 1
Virus classification Edit this classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Peploviricota
Class: Herviviricetes
Order: Herpesvirales
Family: Orthoherpesviridae
Genus: Varicellovirus
Species:
Suid alphaherpesvirus 1
Synonyms[1]
  • Suid herpesvirus 1
  • Pseudorabies virus

Aujeszky's disease, usually called pseudorabies in the United States, is a viral disease in swine that is endemic in most parts of the world. It is caused by Suid herpesvirus 1 (SuHV-1). Aujeszky's disease is considered to be the most economically important viral disease of swine in areas where classical swine fever (hog cholera) has been eradicated.[2] Other mammals, such as cattle, sheep, goats, cats, dogs, and raccoons, are also susceptible. The disease is usually fatal in these animal species.

Research on SuHV-1 in pigs has pioneered animal disease control with genetically modified vaccines. SuHV-1 is now used in model studies of basic processes during lytic herpesvirus infection, and for unravelling molecular mechanisms of herpesvirus neurotropism.[3][4]

  1. ^ "ICTV Taxonomy history: Suid alphaherpesvirus 1". International Committee on Taxonomy of Viruses (ICTV). Retrieved 9 January 2019.
  2. ^ Fenner, Frank J.; Gibbs, E. Paul J.; Murphy, Frederick A.; Rott, Rudolph; Studdert, Michael J.; White, David O. (1993). Veterinary Virology (2nd ed.). Academic Press, Inc. ISBN 978-0-12-253056-2.
  3. ^ Mettenleiter (2008). "Molecular Biology of Animal Herpesviruses". Animal Viruses: Molecular Biology. Caister Academic Press. ISBN 978-1-904455-22-6.
  4. ^ Sandri-Goldin, RM, ed. (2006). Alpha Herpesviruses: Molecular and Cellular Biology. Caister Academic Press. ISBN 978-1-904455-09-7.