Publius Cornelius Lentulus Spinther (c. 100 BC – 47 BC) was a Roman politician and general. Hailing from the patrician family of the Cornelii, he helped suppress the Catilinarian conspiracy during his term as curule aedile in 63 BC and later served as consul in 57 BC. Denied the opportunity to invade Egypt the following year, he nevertheless won some victories in his province of Cilicia and celebrated a triumph over it in 51 BC.
In the run-up to Caesar's civil war, he sided with Pompey and the senate. Captured by Caesar and pardoned at Corfinium in the opening months of the war, he made his way to Greece to join Pompey's forces. He is last attested to in early 47 BC.