Pumiliotoxin 251D

Pumiliotoxin 251D
Names
Preferred IUPAC name
(6Z,8S,8aS)-8-Methyl-6-[(2R)-2-methylhexylidene]octahydroindolizin-8-ol
Other names
Pumiliotoxin 251D
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
KEGG
  • InChI=1S/C16H29NO/c1-4-5-7-13(2)10-14-11-16(3,18)15-8-6-9-17(15)12-14/h10,13,15,18H,4-9,11-12H2,1-3H3/b14-10-/t13-,15+,16+/m1/s1 ☒N
    Key: OKTQTXDNHCOLHT-AJKPHIATSA-N ☒N
  • InChI=1/C16H29NO/c1-4-5-7-13(2)10-14-11-16(3,18)15-8-6-9-17(15)12-14/h10,13,15,18H,4-9,11-12H2,1-3H3/b14-10-/t13-,15+,16+/m1/s1
    Key: OKTQTXDNHCOLHT-AJKPHIATBP
  • O[C@]1(CC(=C\[C@H](C)CCCC)\CN2[C@H]1CCC2)C
Properties
C16H29NO
Molar mass 251.414 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Toxic
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Pumiliotoxin 251D is a toxic organic compound. It is found in the skin of poison frogs from the genera Dendrobates, Epipedobates, Minyobates, and Phyllobates[1][2] and toads from the genus Melanophryniscus.[3] Its name comes from the pumiliotoxin family (PTXs) and its molecular mass of 251 daltons. When the toxin enters the bloodstream through cuts in the skin or by ingestion,[4] it can cause hyperactivity, convulsions, cardiac arrest and ultimately death. It is especially toxic to arthropods (e.g. mosquitoes), even at low (naturally occurring) concentrations.[5]

  1. ^ Cite error: The named reference Vandendriessche was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference Mortari was invoked but never defined (see the help page).
  3. ^ Cite error: The named reference Mebs was invoked but never defined (see the help page).
  4. ^ Cite error: The named reference Factslist was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference Paul was invoked but never defined (see the help page).