Puromycin

Puromycin
Names
IUPAC name
3′-Deoxy-N,N-dimethyl-3′-(O-methyl-L-tyrosinamido)adenosine
Systematic IUPAC name
(2S)-2-Amino-N-{(2S,3S,4R,5R)-5-[6-(dimethylamino)-9H-purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl}-3-(4-methoxyphenyl)propanamide
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
KEGG
MeSH Puromycin
UNII
  • InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1 checkY
    Key: RXWNCPJZOCPEPQ-NVWDDTSBSA-N checkY
  • InChI=1/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1
    Key: RXWNCPJZOCPEPQ-NVWDDTSBBO
  • O=C(N[C@@H]3[C@H](O[C@@H](n2cnc1c2ncnc1N(C)C)[C@@H]3O)CO)[C@@H](N)Cc4ccc(OC)cc4
Properties
C22H29N7O5
Molar mass 471.50956
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Puromycin is an antibiotic protein synthesis inhibitor which causes premature chain termination during translation.