| Pyoderma gangrenosum | |
|---|---|
 | |
| Pyoderma gangrenosum on the leg of a person with ulcerative colitis. | |
| Specialty | Dermatology  |
| Usual onset | 40s or 50s[1] |
| Treatment | Corticosteroids, ciclosporin, infliximab, canakinumab[2] |
Pyoderma gangrenosum is a rare, inflammatory skin disease where painful pustules or nodules become ulcers that progressively grow.[3] Pyoderma gangrenosum is not infectious.[3]
Treatments may include corticosteroids, ciclosporin, infliximab, or canakinumab.[2]
The disease was identified in 1930. It affects approximately 1 person in 100,000 in the population. Though it can affect people of any age, it mostly affects people in their 40s and 50s.[1]
- ^ a b Jackson JM, Callen JP (April 23, 2012). Elston DM (ed.). "Pyoderma Gangrenosum". EMedicine.
- ^ a b Partridge AC, Bai JW, Rosen CF, Walsh SR, Gulliver WP, Fleming P (August 2018). "Effectiveness of systemic treatments for pyoderma gangrenosum: a systematic review of observational studies and clinical trials". The British Journal of Dermatology. 179 (2): 290–295. doi:10.1111/bjd.16485. PMID 29478243. S2CID 3504429.
- ^ a b Ruocco E, Sangiuliano S, Gravina AG, Miranda A, Nicoletti G (September 2009). "Pyoderma gangrenosum: an updated review". Journal of the European Academy of Dermatology and Venereology. 23 (9): 1008–17. doi:10.1111/j.1468-3083.2009.03199.x. PMID 19470075. S2CID 29773727.