QST (genetics)

In quantitative genetics, QST is a statistic intended to measure the degree of genetic differentiation among populations with regard to a quantitative trait. It was developed by Ken Spitze in 1993.[1] Its name reflects that QST was intended to be analogous to the fixation index for a single genetic locus (FST).[2][3] QST is often compared with FST of neutral loci to test if variation in a quantitative trait is a result of divergent selection or genetic drift, an analysis known as QST–FST comparisons.

  1. ^ Spitze K (October 1993). "Population structure in Daphnia obtusa: quantitative genetic and allozymic variation". Genetics. 135 (2): 367–374. doi:10.1093/genetics/135.2.367. PMC 1205642. PMID 8244001.
  2. ^ Whitlock MC (April 2008). "Evolutionary inference from QST". Molecular Ecology. 17 (8): 1885–1896. doi:10.1111/j.1365-294X.2008.03712.x. PMID 18363667.
  3. ^ McKay JK, Latta RG (June 2002). "Adaptive population divergence: markers, QTL and traits". Trends in Ecology & Evolution. 17 (6): 285–291. doi:10.1016/S0169-5347(02)02478-3.