RIMS1

RIMS1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CSS
Identifiers
Aliases	RIMS1, CORD7, RAB3IP2, RIM, RIM1, regulating synaptic membrane exocytosis 1
External IDs	OMIM: 606629; MGI: 2152971; HomoloGene: 128399; GeneCards: RIMS1; OMA:RIMS1 - orthologs
RNA expression pattern
	n/a
	n/a
	More reference expression data
Gene ontology
Molecular function	GTPase regulator activity; metal ion binding; protein binding; transmembrane transporter binding; RNA binding;
Cellular component	cytosol; membrane; plasma membrane; synapse; presynaptic active zone; cell junction; presynaptic membrane; cytoskeleton of presynaptic active zone; presynaptic active zone cytoplasmic component;
Biological process	cell differentiation; response to stimulus; synaptic vesicle exocytosis; positive regulation of inhibitory postsynaptic potential; membrane fusion; regulation of neurotransmitter secretion; secretion; glutamate secretion; positive regulation of gene expression; positive regulation of excitatory postsynaptic potential; positive regulation of dendrite extension; regulated exocytosis; intracellular protein transport; neurotransmitter transport; neurotransmitter secretion; visual perception; calcium-ion regulated exocytosis; exocytosis; regulation of catalytic activity; regulation of membrane potential; calcium ion-regulated exocytosis of neurotransmitter; regulation of synaptic vesicle exocytosis; transport; regulation of synaptic plasticity; positive regulation of synaptic transmission; protein-containing complex assembly; acrosomal vesicle exocytosis;
	Sources:Amigo / QuickGO
Orthologs
	22999
	116837
	ENSG00000079841
	ENSMUSG00000041670
	Q86UR5
	Q99NE5
NM_001168407; NM_001168408; NM_001168409; NM_001168410; NM_001168411;
	NM_014989
	NM_001012623; NM_001012624; NM_001012625; NM_053270; NM_183018
NP_001161879; NP_001161880; NP_001161881; NP_001161882; NP_001161883;
	NP_055804; NP_001337340; NP_001337341; NP_001337342; NP_001337343; NP_001337344; NP_001337345; NP_001337346; NP_001337347; NP_001337348; NP_001337349; NP_001337350; NP_001337351; NP_001337352; NP_001337353; NP_001337354; NP_001337355; NP_001337356; NP_001337357; NP_001337358; NP_001337359; NP_001337360; NP_001337361; NP_001337362; NP_001337363; NP_001337364; NP_001337365; NP_001337366; NP_001337367; NP_001337368; NP_001337369; NP_001337370; NP_001337371; NP_001337372; NP_001337373; NP_001337374; NP_001337375; NP_001337376; NP_001337377; NP_001337378; NP_001337379; NP_001337381; NP_001337383; NP_001337384; NP_001337385; NP_001337386; NP_001337387; NP_001337388; NP_001337389; NP_001337390; NP_001337391; NP_001337392; NP_001337393; NP_001337394; NP_001337395; NP_001337396; NP_001337397; NP_001337398; NP_001337399; NP_001337400; NP_001337401; NP_001337402; NP_001337403
	NP_001012641; NP_001012642; NP_001012643; NP_444500; NP_898839
	Wikidata
View/Edit Human	View/Edit Mouse

Regulating synaptic membrane exocytosis protein 1 is a protein that in humans is encoded by the RIMS1 gene.^[3]^[4]^[5]

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (September 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.
^ Coppola T, Magnin-Luthi S, Perret-Menoud V, Gattesco S, Schiavo G, Regazzi R (August 2001). "Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin". J Biol Chem. 276 (35): 32756–62. doi:10.1074/jbc.M100929200. PMID 11438518.
^ "Entrez Gene: RIMS1 regulating synaptic membrane exocytosis 1".

[1] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[2] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9205841-3] Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (September 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.

[pmid11438518-4] Coppola T, Magnin-Luthi S, Perret-Menoud V, Gattesco S, Schiavo G, Regazzi R (August 2001). "Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin". J Biol Chem. 276 (35): 32756–62. doi:10.1074/jbc.M100929200. PMID 11438518.

[entrez-5] "Entrez Gene: RIMS1 regulating synaptic membrane exocytosis 1".

[1]

[2]

[3]

[4]

[5]