RRAS

RRAS
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2FN4
Identifiers
Aliases	RRAS, related RAS viral (r-ras) oncogene homolog, R-Ras, RAS related
External IDs	OMIM: 165090; MGI: 98179; HomoloGene: 4565; GeneCards: RRAS; OMA:RRAS - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	49,640,143 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	44,671,071 bp
RNA expression pattern
	Top expressed in
	right coronary artery; ; popliteal artery; ; tibial arteries; ; thoracic aorta; ; ascending aorta; ; Descending thoracic aorta; ; left coronary artery; ; gastric mucosa; ; left uterine tube; ; muscle layer of sigmoid colon;
	Top expressed in
	tunica media of zone of aorta; ; carotid body; ; external carotid artery; ; ascending aorta; ; right lung; ; white adipose tissue; ; right lung lobe; ; left lung; ; aortic valve; ; tunica adventitia of aorta;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GDP binding; protein-containing complex binding; GTP binding; protein binding; GTPase activity;
Cellular component	membrane; focal adhesion; plasma membrane; extracellular exosome; intracellular anatomical structure;
Biological process	positive regulation of angiogenesis; negative regulation of cell migration; regulation of protein kinase B signaling; regulation of ERK1 and ERK2 cascade; leukocyte differentiation; Ras protein signal transduction; face morphogenesis; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	6237
	20130
	ENSG00000126458
	ENSMUSG00000038387
	P10301
	P10833
	NM_006270
	NM_009101; NM_001360132; NM_001360133
	NP_006261
	NP_033127; NP_001347061; NP_001347062
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein R-Ras is a protein that in humans is encoded by the RRAS gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000126458 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038387 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lowe DG, Capon DJ, Delwart E, Sakaguchi AY, Naylor SL, Goeddel DV (February 1987). "Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes". Cell. 48 (1): 137–46. doi:10.1016/0092-8674(87)90364-3. PMID 3098437. S2CID 22622027.
^ "Entrez Gene: RRAS related RAS viral (r-ras) oncogene homolog".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000126458 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038387 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid3098437-5] Lowe DG, Capon DJ, Delwart E, Sakaguchi AY, Naylor SL, Goeddel DV (February 1987). "Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes". Cell. 48 (1): 137–46. doi:10.1016/0092-8674(87)90364-3. PMID 3098437. S2CID 22622027.

[entrez-6] "Entrez Gene: RRAS related RAS viral (r-ras) oncogene homolog".

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