RTN3

RTN3
Identifiers
Aliases	RTN3, ASYIP, HAP, NSPL2, NSPLII, RTN3-A1, reticulon 3
External IDs	OMIM: 604249; MGI: 1339970; HomoloGene: 24934; GeneCards: RTN3; OMA:RTN3 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	63,759,891 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	7,460,646 bp
RNA expression pattern
	Top expressed in
	Brodmann area 9; ; prefrontal cortex; ; right frontal lobe; ; anterior cingulate cortex; ; ganglionic eminence; ; pons; ; ventricular zone; ; hypothalamus; ; C1 segment; ; amygdala;
	Top expressed in
	facial motor nucleus; ; anterior horn of spinal cord; ; central gray substance of midbrain; ; nucleus of stria terminalis; ; primary motor cortex; ; medial vestibular nucleus; ; prefrontal cortex; ; motor neuron; ; dorsomedial hypothalamic nucleus; ; medial dorsal nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; Golgi membrane; Golgi apparatus; endoplasmic reticulum; membrane; endoplasmic reticulum membrane; plasma membrane; extracellular space; synapse;
Biological process	endoplasmic reticulum tubular network organization; viral process; vesicle-mediated transport; apoptotic process; endoplasmic reticulum tubular network formation;
	Sources:Amigo / QuickGO
Orthologs
	10313
	20168
	ENSG00000133318
	ENSMUSG00000024758
	O95197
	Q9ES97
NM_001265589; NM_001265590; NM_001265591; NM_006054; NM_201428;
	NM_201429; NM_201430
NM_001003930; NM_001003933; NM_001003934; NM_001271486; NM_001271487;
	NM_053076
NP_001252518; NP_001252519; NP_001252520; NP_006045; NP_958831;
	NP_958832; NP_958833
	NP_001003933; NP_001003934; NP_001258415; NP_001258416; NP_444306
	Wikidata
View/Edit Human	View/Edit Mouse

Reticulon-3 is a protein that in humans is encoded by the RTN3 gene.^[5]^[6]

The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues (see, e.g., RTN1; MIM 600865).[supplied by OMIM]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000133318 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024758 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Moreira EF, Jaworski CJ, Rodriguez IR (Jul 1999). "Cloning of a novel member of the reticulon gene family (RTN3): gene structure and chromosomal localization to 11q13". Genomics. 58 (1): 73–81. doi:10.1006/geno.1999.5807. PMID 10331947.
^ ^a ^b "Entrez Gene: RTN3 reticulon 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000133318 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024758 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10331947-5] Moreira EF, Jaworski CJ, Rodriguez IR (Jul 1999). "Cloning of a novel member of the reticulon gene family (RTN3): gene structure and chromosomal localization to 11q13". Genomics. 58 (1): 73–81. doi:10.1006/geno.1999.5807. PMID 10331947.

[entrez-6] "Entrez Gene: RTN3 reticulon 3".

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