Leucine-rich repeat receptor-like protein kinase | |
---|---|
Identifiers | |
Symbol | LRRK |
Membranome | 737 |
Leucine-rich repeat receptor-like protein | |
---|---|
Identifiers | |
Symbol | LRRP |
Membranome | 605 |
TIR-NBS-LRR disease resistance proteins | |
---|---|
Identifiers | |
Symbol | TIR-NBS-LRR |
Membranome | 1343 |
TIR domain plant proteins | |
---|---|
Identifiers | |
Symbol | TIRP |
Membranome | 1344 |
Resistance genes (R-Genes) are genes in plant genomes that convey plant disease resistance against pathogens by producing R proteins. The main class of R-genes consist of a nucleotide binding domain (NB) and a leucine rich repeat (LRR) domain(s) and are often referred to as (NB-LRR) R-genes or NLRs.[1] Generally, the NB domain binds either ATP/ADP or GTP/GDP. The LRR domain is often involved in protein-protein interactions as well as ligand binding. NB-LRR R-genes can be further subdivided into toll interleukin 1 receptor (TIR-NB-LRR) and coiled-coil (CC-NB-LRR).[2]
Resistance can be conveyed through a number of mechanisms including:
Once the R protein has detected the presence of a pathogen, the plant can mount a defence against the pathogen. Because R genes confer resistance against specific pathogens, it is possible to transfer an R gene from one plant to another and make a plant resistant to a particular pathogen.
Many plant resistance proteins are single-pass transmembrane proteins that belong to receptor kinases and Toll-like receptors. R genes are of large interest in crop breeding, providing a large part of the immunity required by agricultural pathosystems.[1]
Hafeez-et-al-2021
was invoked but never defined (see the help page).