Rachel E. Klevit

Rachel E. Klevit
Alma materReed College, BA, 1978
Oxford University, D.Phil, 1981

Rachel E. Klevit is professor of biochemistry, adjunct professor of chemistry, and adjunct professor of pharmacology at the University of Washington. She holds the Edmond H. Fischer-Washington Research Foundation Endowed Chair in Biochemistry. Klevit's research focuses on molecular interactions in human diseases and includes research on BRCA1, the protein ubiquitination system, and human heat shock proteins.[1][2][3]

  1. ^ Christensen, DE; Brzovic, PS; Klevit, RE (October 2007). "E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages". Nature Structural & Molecular Biology. 14 (10): 941–8. doi:10.1038/nsmb1295. PMID 17873885.
  2. ^ Vittal, V; Wenzel, DM; Brzovic, PS; Klevit, RE (September 2013). "Biochemical and structural characterization of the ubiquitin-conjugating enzyme UBE2W reveals the formation of a noncovalent homodimer". Cell Biochemistry and Biophysics. 67 (1): 103–10. doi:10.1007/s12013-013-9633-5. PMC 3758794. PMID 23709311.
  3. ^ Delbecq, SP; Rosenbaum, JC; Klevit, RE (21 July 2015). "A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers". Biochemistry. 54 (28): 4276–84. doi:10.1021/acs.biochem.5b00490. PMC 4512712. PMID 26098708.